Botulinum toxin

What is it?

Botulinum toxin (BT) is a protein, which is produced by Clostridium botulinum (bacteria). For decades it has been used in medicine for therapeutic purposes. It is approved by the US Food and Drug Administration and is mostly used for slight corrections of the facial mimic wrinkles. It is also part of the hyperhydrosis treatment.

How does it work?

It blocks the acetyl-mediated transmission of impulses from the neuron to the muscle fibers. As a result, the muscle remains relaxed. When the muscle doesn't contract it cannot move the upper skin. This prevents the emerging of new wrinkles, while old wrinkles tend to disappear over time. The effect is temporary and totally reversible. The aesthetic industry uses extremely small doses of BT, which do not impact the overall health condition of the patients.

BT also blocks the overstimulation of the sweat glands, thus reducing sweating palms, feet, and underarms. BT injection is the most common way to fight mimic wrinkles. This medical procedure is carried only by licensed dermatologists or plastic surgeons. They are also responsible for the paperwork that goes with BT injection.

Where can BT be applied?

  • on the forehead – horizontal wrinkles
  • between the eyebrows
  • around the eyes (eye wrinkles)
  • on both sides of the nose (bunny lines)
  • eyebrows lifting
  • feet, palms, and underarms (when the patient suffers from hyperhydrosis)

Other conditions:

  • around the mouth (lip/barcode wrinkles)
  • smoking wrinkles
  • marionette wrinkles
  • chin wrinkles
  • neck wrinkles


Does it hurt? Any side effects?

This is an extremely quick procedure and patients feel almost no pain. We use super tiny needles in an effort to cause as less discomfort as possible. Some patients with low pain thresholds require local anesthesia with crème or ice.

The most common side effects include headache and hematomas, which usually disappear within days.

Cases not suitable for BT

BT injection is not done on patients with acute infectious diseases, blood clotting disorders, neurological disorders (including myasthenia gravis), and BT allergies. It is also forbidden for patients who undergo anticoagulant therapy, intake baclofen, as well as pregnant and lactating women.

Two weeks prior to the procedure avoid aspirin, vitamin E, omega-3 fatty acids, ginkgo biloba, Panax, and ibuprofen. Do not drink alcohol two days before the treatment.

After the procedure:

  • do not massage the treated area
  • do not train at least 24h
  • avoid hot places such as sauna and solarium
  • avoid sunlight
  • do not lie for at least six hours
  • do not consume alcohol
  • two weeks after the procedure there is a checkup

How long does the BT effect last?

Wrinkles usually disappear 2-3 days after the injection but the visible effect needs one to two weeks to fully take place. If you are not satisfied with the result, correction is possible. In any case, the effect lasts for at least 3-6 months depending on the area and each individual. You can reverse the effect of BT and your muscles will be able to move once again. Every next injection extends the period in which BT's effect lasts. We recommend at least 3-months break between separate interventions.

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